Standard units for expressing drug concentrations in biological fluids.
نویسندگان
چکیده
منابع مشابه
Utility of clinical chemical determinations of drug concentrations in biological fluids.
latrogenic drug toxicity has become a major medical problem. An approach to avoiding adverse reactions arising from drug accumulation is suggested and explored in depth. Large differences in the rates at which individuals metabolize several commonly used drugs are reviewed, because they illustrate the dangers of prescribing drugs solely according to body weight or surface area, and they emphasi...
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Concentrations of unbound drug in the interstitial fluid of the brain are not rapidly measured in vivo. Therefore, measurement of total drug levels, i.e., the amount of drug per gram of brain, has been a common but unhelpful practice in drug discovery programs relating to central drug effects. This study was designed to evaluate in vitro techniques for faster estimation of unbound drug concentr...
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ژورنال
عنوان ژورنال: British Journal of Clinical Pharmacology
سال: 1983
ISSN: 0306-5251
DOI: 10.1111/j.1365-2125.1983.tb02136.x